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Why Do Antibiotics Cause Me Pain?

6/17/2017

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I found an interesting article posted in 2012 in Vitality 101.  There numerous studies on the internet that can attain to such theories. One such specific experiment, if you enjoy reading medical journals, is Diagnosis and Treatment of Chronic Mycoplasmal Infections in Fibromyalgia and Chronic Fatigue.  This was written in 1998, which only cries out concern as to why there isn't more extended studies being completed. I am sure it is due to the multi-billion dollar medical facilities that provide our daily pills.  After all, chronic illness is BIG business these days.  

I have always been speculative when I am provided antibiotics.  After all, I have extreme sensitivities to any type of matter that is ingested and doesn't agree well with my system.  Antibiotics will cause extreme joint pain, all over fatigue, and flu-like feelings.  I am always calling my doctor back for a new prescription because the usual one is so intolerable.  Every time I am told, by my practitioner, that I should stop them immediately and start the new script the following day.  But the funny thing is, when I do stop it, for the next several days, my body aches and pains subside, and I have a higher clarity of thinking.  Something is not connecting I always assume.

It wasn't until my recent bought with pancreatitis when I was hooked up to so many IV's which contained various drips and antibiotics and antivirals that I felt an epiphany.  For when it was all over I had a normal body for three weeks free of fibromyalgia. Oh sure, my pancreas was sore, but I had a feeling of utopia, if that makes an sense in such a condition, that I may be free of chronic illness.  

Slowly my symptoms returned leaving me as an old overused nest. But some of the more heightened issues like environmental sensitivities left.  So did many of the chemical sensitivities I experienced for five years.  I found I could last longer throughout the day needing less respite, too.

Here's some excerpts of From Fatigue to Fantastic, vitality 101, that are much easy reading than the journal labeled above: 

Because of the immune dysfunction present in CFS and Fibromyalgia, most of us have had not one, but many different infections associated with our illness. These include Yeast/Candida, Viral infections, Parasites, and Antibiotic Sensitive Infections (including Lyme and many others). Unfortunately, the tests we have available are largely geared toward picking up early infections, and miss most chronic infections. We have discussed viral infections and the problems with lab testing elsewhere. In addition, Professor Montoya will be presenting his placebo controlled research results later this month on using Valcyte to address CFS at the Baltimore HHV-6 conference. I suspect the results are positive as the drug company offered me $1,500 to come to a meeting discussing the results (I declined), but I look forward to seeing the results as we have found Valcyte to be very helpful in those with HHV 6 IgG blood tests of 1:320 or higher.

Some infections (especially yeast/Candida), however, need to be addressed for you to recover. Some have chronic Lyme, though testing for this is very unreliable (see Lyme testing). In addition to addressing Candida, Lyme, and occasionally viruses and parasites, a subset of people with CFS/FMS need long term antibiotic therapy. I find this is the case if any of the following are present:
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  1. A fever over 98.6°F—even 99°F—and/or
  2. Chronic lung congestion,
  3. Recurrent scalp sores which scab,
  4. A history of bad reactions to several different antibiotics (people misinterpret the die-off reaction as being an allergic reaction),
  5. A history of your CFS/FMS transiently improving in the past when given an antibiotic,
  6. Severe vertigo—this is when you feel like you or the room is spinning in a circle and is not to be confused with the disequilibrium experienced by most of us with CFS,
  7. Severe night sweats that persist after addressing the Candida and hormonal deficiencies.
If you have any of these, you may benefit from a trial of antibiotics. 

People with these symptoms seem to be more likely to have infections that respond to special antibiotics. Fortunately, Lyme, mycoplasma and chlamydia infections, as well as many other infections that are difficult to test for in CFS, are often sensitive to the right antibiotics. The antibiotics most likely to affect these organisms are the following:
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  • Doxycycline or preferably minocycline, usually at dosages of 100 milligrams twice a day. These two antibiotics are in the tetracycline family. They are very effective against a number of unusual organisms (for example, Lyme disease). They sometimes cause some stomach upset. If this occurs, take the medicine with food and a full glass of water or lower the dose. They should not be given to children under eight years old because they can cause permanent staining of the teeth.
  • Ciprofloxacin (Cipro), usually 500-750 milligrams twice a day. Although expensive, this is usually a well-tolerated antibiotic. It has a very wide range of effectiveness against a large number of organisms. Cipro has an additional benefit for men, as it also addresses any hidden prostate infections, as does doxycycline. You should not take oral magnesium or any supplement containing magnesium within 4 to 6 hours of taking Cipro or you may not absorb the Cipro as completely. A small percent of the population has a genetic defect that prevents them from breaking down Cipro. In this group, taking Cipro can actually trigger FMS and this family of antibiotics should be avoided if you have a family member that developed fibromyalgia after taking Cipro. Cipro should only be used in adults.
  • Azithromycin (Zithromax), 250-600 milligrams a day taken with food, or clarithromycin (Biaxin), 500 milligrams twice a day, taken on an empty stomach. These antibiotics are in the erythromycin family. Zithromax tends to be fairly well tolerated. Biaxin is more likely to cause a bit of nausea in some patients, but it is usually also well tolerated. They may work against infections missed by doxycycline and Cipro. Begin with this antibiotic if you have scalp or skin sores or scabs.

Although all of these antibiotics can be effective, it is not uncommon for infections that are sensitive to the erythromycin antibiotics (Zithromax or Biaxin) to be resistant to tetracycline antibiotics (doxycycline, minocycline) and Cipro, and vice-versa. Therefore, it is best to try either doxycycline or Cipro first. If they are not effective, then try the Zithromax or Biaxin. The antibiotic should be taken for at least six months. If there is no improvement in four months, switch to or add the other antibiotic or simply stop the therapy.

It is very common to get what is called a Herxheimer (die-off) reaction that includes chills, fever, night sweats, and general worsening of CFS/FMS symptoms when the antibiotic first kills off the infection. Many people mistakenly confuse these with an allergic reaction. These symptoms can be severe and last for weeks. Stop the antibiotic and let the die-off reaction subside. Then resume the antibiotic at a much lower dose (e.g., 25 mg of Minocycline every other day) and work the dose up slowly as able. The Nicholsons, who pioneered this therapy of antibiotic sensitive infections, note that if you have been sick for years, it is unlikely you will recover in less than one year of therapy, so you should not be alarmed by symptoms that return or worsen temporarily.

One more "antibiotic sensitive infection" deserves mention. If spastic colon symptoms persist after addressing yeast and parasites, consider addressing "SIBO" (Small Intestine Bacterial Overgrowth), which is common in CFS/FMS and another key cause of bowel symptoms. Having a low thyroid increases your risk of SIBO. Research has shown that addressing the issue empirically with the antibiotic Rifaximin 400 mg 3x day for 10 days can result in long lasting improvement of the symptoms of irritable bowel syndrome/spastic colon.

Unfortunately, most physicians are not familiar with the immune function seen in CFS/FMS and will not prescribe anything if the tests are negative (even though the tests are not reliable). To find a physician who knows how to address these infections, find a holistic doctor or see a Fibromyalgia and Fatigue Center physician. CFS and FMS are very addressable, and addressing these hidden infections is one more piece of the puzzle!

Of course, do be careful and monitor your symptoms with  your primary provider.  There are those group of people that have a genetic predisposition for adverse affects of cipro.  This is due to a neurological defect. As for me, I am just finishing a dose of ciprofloxacin and have noted several new minimization of previous symptoms.  I am curious to see if they will last like my last doses.  I can tell you as of the first couple of days i was ready to throw in the towel, so to speak, as symptoms were painful.  Now that I am on day five I am noticing less trauma and more energy and a bit more clarity in my everyday tasks.  

​Please keep in mind, that if you have a huge infection, like bronchitis, and are prescribed antibiotics; you may not feel such relief as the drug may be cursing through your system only removing those harboring pathogens of the present infection.  


Big Al's Aquarium Services, Ltd.
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