In fact, FMS and CFS are often mentioned interchangeably. While research indicates that between 50 to 70 percent of individuals with fibromyalgia also fit the criteria of CFS, here are some major distinctions between them:
- Fibromyalgia can often be traced to an injury, or to physical or emotional trauma. CFS, on the other hand, is characterized by the onset of mysterious flu-like symptoms.
- Fibromyalgia patients have abnormally high levels of chemicals such as serotonin and substance P, which are related to pain signals.
- CFS sufferers do not have the tender trigger points characteristic of FMS.
- Most fibromyalgia research revolves around pain transmission and deep sleep analysis, whereas chronic fatigue syndrome research tends to revolve around viral and immune system factors.