Your Fibro Support
Like Us on Facebook!
  • Fibro Relief Blog
  • Products
  • Recipes
  • Home
  • Sign Up - Share Your Tips
  • Archives

Antiviral Treatment IMC-1 Shows Promise in Phase 2 Fibromyalgia Trial

3/18/2017

0 Comments

 
Picture
IMC-1, a combination treatment of two drugs targeting the herpes virus, may be a safe and effective treatment for patients with fibromyalgia, according to the results of a Phase 2 trial developed by Innovative Med Concepts.

Results were published in an article titled “A Famciclovir + Celecoxib Combination Treatment Is Safe And Efficacious In The Treatment Of Fibromyalgia” in the Journal of Pain Research.

“Infections and other stressors have been implicated in the development of fibromyalgia,” researchers wrote in their report. “We hypothesized that these stressors could result in recurrent reactivations of latent herpes virus infections, which could lead to the development of fibromyalgia. This study evaluated … IMC-1, active against suspected herpes virus reactivation and infection, for the treatment of fibromyalgia.”

The PRID-201 study (NCT01850420) enrolled 143 patients with fibromyalgia at 12 research centers in the U.S. to evaluate the effects of IMC-1 — a combination treatment of the antiviral drug famciclovir and the anti-inflammatory drug celecoxib (brand name Celebrex).

Results showed that, after 16 weeks of treatment, patients receiving IMC-1 had a decrease in fibromyalgia-associated pain compared to patients on a placebo. Half of the patients assigned to receive IMC-1 presented at least a 30% decline in pain, and 38% presented at least a 50% decrease in pain.

IMC-1 treatment also improved the scores of two questionnaires, the Patient Global Impression of Change (PGIC) and the revised disease-specific Fibromyalgia Impact Questionnaire (FIQ-R), as well as the patient’s self-reported fatigue.

IMC-1 was well-tolerated by patients. Common side effects included gastrointestinal (29% vs 42.5% in the placebo group) and nervous system (17.4% vs. 23.3%) events, but these were more frequently seen in patients in the placebo group than in those in the treatment group. Also, most patients adhered to the complete treatment compared to the placebo (82.6% vs. 60.8%).

Taken together, the results showed that suppressing latent herpes viruses may significantly improve fibromyalgia-related symptoms, and that the treatment is a safe and effective approach to reduce pain in this patient population.
​
Based on several positive results, the U.S. Food and Drug Administration (FDA) granted Fast Track designation to IMC-1 in 2016 to support and accelerate the development of this therapy for those in need.
According to a press release, Innovative Med Concepts plans to conduct a Phase 3 trial using an improved IMC-1 later in 2017. - Shared from Fibromyalgia News today

Beach Destinations Sale at never before fares. Get Flat $15 Off using Coupon Code SFBEACH15.
0 Comments



Leave a Reply.

    RSS Feed

    Wal-Mart.com USA, LLC
    Improve your mental health in the most convenient and affordable way with an online therapy at Talkspace.com!
    MyUS.com
    Good Sam Travel Assist
    Gaia
    Panda Planner

    Author

    Valerie utilizes an extensive amount of research producing this blog.  Categories are purposely set up in stages, rather than topics, so you can easily implement one step at a time. 

    Archives

    September 2022
    May 2022
    January 2022
    November 2021
    October 2021
    September 2021
    July 2021
    June 2021
    May 2021
    April 2021
    March 2021
    February 2021
    January 2021
    December 2020
    November 2020
    October 2020
    September 2020
    August 2020
    June 2020
    May 2020
    April 2020
    March 2020
    February 2020
    January 2020
    December 2019
    November 2019
    October 2019
    September 2019
    August 2019
    July 2019
    June 2019
    May 2019
    April 2019
    March 2019
    February 2019
    January 2019
    December 2018
    November 2018
    October 2018
    September 2018
    August 2018
    July 2018
    June 2018
    May 2018
    April 2018
    March 2018
    February 2018
    January 2018
    December 2017
    November 2017
    October 2017
    September 2017
    August 2017
    July 2017
    June 2017
    May 2017
    April 2017
    March 2017
    February 2017
    January 2017
    December 2016
    November 2016
    October 2016
    September 2016
    August 2016
    July 2016
    June 2016
    May 2016
    April 2016
    March 2016
    February 2016
    January 2016
    December 2015
    November 2015
    October 2015
    September 2015
    August 2015
    July 2015
    June 2015
    May 2015
    April 2015
    March 2015
    February 2015
    January 2015
    December 2014
    November 2014
    October 2014
    September 2014
    August 2014
    July 2014
    June 2014
    May 2014
    April 2014
    March 2014
    February 2014
    January 2014
    December 2013
    November 2013
    October 2013
    September 2013
    August 2013
    July 2013
    June 2013
    May 2013
    April 2013
    March 2013
    February 2013
    January 2013
    December 2012
    November 2012
    October 2012
    September 2012
    August 2012
    July 2012
    June 2012
    May 2012
    April 2012

    Categories

    All
    Alternative Therapies
    A New Beginning
    Apps
    Avoiding Flare Ups
    Breathing
    Cleaning
    Cultured Foods
    Dealing With Aftershocks
    Depression
    Diet
    Exercise
    Finding Relief
    Good Reads
    Great Flicks
    Grief
    Grounding
    Health Care
    Holiday Madness
    Insurance
    Intermittent Fasting
    In The Beginning
    Maintenance
    Medical
    Medical Information
    Meditation
    Memory
    Mental Well Being
    Minimalism
    Natural Body Cleansers
    Natural Products
    Paleo
    Prayer
    Recipes
    Resources
    Season Pick
    Sleep
    Social Security Disability
    Soup
    Stress
    Supplements
    Tapping
    Twin Flame
    Videos
    Welcome

Powered by Create your own unique website with customizable templates.